Do-Hee Kim Selected Research

15-deoxyprostaglandin J2

9/2020	15-Deoxy-Δ12,14-prostaglandin J2 Induces Epithelial-to-mesenchymal Transition in Human Breast Cancer Cells and Promotes Fibroblast Activation.
3/2019	15-Deoxy-Δ12,14-prostaglandin J2 up-regulates the expression of 15-hydroxyprostaglandin dehydrogenase through DNA methyltransferase 1 inactivation.
1/2018	15-Deoxy-Δ12,14-prostaglandin J2 activates PI3K-Akt signaling in human breast cancer cells through covalent modification of the tumor suppressor PTEN at cysteine 136.
10/2016	15-Deoxy-Δ12,14-prostaglandin J2 stabilizes hypoxia inducible factor-1α through induction of heme oxygenase-1 and direct modification ofprolyl-4-hydroxylase 2.
4/2009	15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS.

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Do-Hee Kim Research Topics

Disease

41	Neoplasms (Cancer) 03/2024 - 04/2008
23	Breast Neoplasms (Breast Cancer) 03/2022 - 12/2004
16	Carcinogenesis 05/2024 - 01/2009
15	Inflammation (Inflammations) 05/2024 - 04/2008
7	Tuberculosis (Tuberculoses) 01/2024 - 08/2017
6	Colonic Neoplasms (Colon Cancer) 01/2023 - 04/2014
6	Stomach Neoplasms (Stomach Cancer) 01/2020 - 01/2005
5	Neoplasm Metastasis (Metastasis) 01/2022 - 04/2009
5	Renal Cell Carcinoma (Grawitz Tumor) 01/2021 - 05/2016
5	Hypertension (High Blood Pressure) 01/2021 - 11/2017
4	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2018
4	Neurogenic Inflammation 01/2021 - 11/2017
4	Colitis 05/2020 - 01/2017
3	Infections 03/2021 - 01/2016
3	Hypoxia (Hypoxemia) 12/2020 - 01/2016
2	Hepatocellular Carcinoma (Hepatoma) 01/2023 - 12/2020
2	Triple Negative Breast Neoplasms 12/2019 - 01/2014
2	Pheochromocytoma 08/2018 - 08/2011
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 03/2018 - 01/2017
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2024
1	Lung Neoplasms (Lung Cancer) 03/2024
1	Poisoning 02/2023
1	Burns 02/2022

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 03/2024 - 12/2004
8	Transcription Factors (Transcription Factor)IBA 01/2023 - 12/2016
7	PhytochemicalsIBA 12/2023 - 01/2018
6	EnzymesIBA 12/2023 - 04/2008
6	Messenger RNA (mRNA)IBA 01/2023 - 01/2018
5	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 05/2024 - 04/2008
5	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 12/2020 - 01/2016
5	15-deoxyprostaglandin J2IBA 09/2020 - 04/2009
5	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2020 - 10/2016
4	Anti-Bacterial Agents (Antibiotics)IBA 01/2024 - 08/2017
4	Estrogen ReceptorsIBA 03/2022 - 01/2019
4	Dextran SulfateIBA 12/2020 - 01/2017
4	ProstaglandinsIBA 09/2020 - 12/2004
4	DNA (Deoxyribonucleic Acid)IBA 07/2020 - 08/2011
4	Heme Oxygenase-1IBA 12/2018 - 04/2009
4	CurcuminIBA 03/2018 - 01/2017
3	Conditioned Culture MediaIBA 03/2022 - 01/2018
3	CytokinesIBA 03/2022 - 01/2018
3	Phosphotransferases (Kinase)IBA 01/2022 - 03/2012
3	Sirtuin 1IBA 01/2022 - 01/2018
3	Cysteine (L-Cysteine)FDA Link 01/2022 - 01/2018
3	thymoquinoneIBA 01/2021 - 10/2019
3	Glutathione (Reduced Glutathione)IBA 01/2020 - 08/2011
3	Glutamate-Cysteine LigaseIBA 01/2020 - 08/2011
3	ginsenoside Rg3IBA 07/2019 - 06/2013
3	salvinIBA 12/2016 - 01/2016
2	NF-E2-Related Factor 2IBA 03/2024 - 03/2021
2	AntioxidantsIBA 03/2024 - 12/2020
2	Tyrosine Kinase InhibitorsIBA 03/2024 - 01/2024
2	LipidsIBA 12/2023 - 05/2023
2	Drinking WaterIBA 02/2023 - 05/2020
2	sulforaphaneIBA 05/2022 - 08/2014
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 03/2022 - 01/2020
2	Extracellular Matrix ProteinsIBA 03/2022 - 01/2018
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2022 - 01/2018
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2022 - 01/2017
2	Serine (L-Serine)FDA Link 01/2022 - 01/2020
2	LigandsIBA 03/2021 - 10/2019
2	NeuropeptidesIBA 01/2021 - 01/2018
2	AzoxymethaneIBA 12/2020 - 05/2020
2	Estrogens (Estrogen)FDA Link 12/2020 - 01/2019
2	Estrogen Receptor betaIBA 12/2020 - 01/2019
2	AntitoxinsIBA 07/2020 - 08/2017
2	Opioid Analgesics (Opioids)IBA 02/2020 - 11/2017
2	Protein Isoforms (Isoforms)IBA 01/2020 - 03/2012
2	ResveratrolIBA 01/2020 - 01/2018
2	GenisteinIBA 12/2019 - 10/2014
2	IsoflavonesIBA 12/2019 - 10/2014
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2019 - 03/2018
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2018 - 01/2017
2	Arachidonic Acid (Vitamin F)IBA 01/2018 - 04/2008
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 11/2012 - 04/2008
2	multidrug resistance-associated protein 1IBA 08/2011 - 08/2009
2	eupatilinIBA 12/2010 - 01/2005
1	Gefitinib (Iressa)FDA Link 03/2024
1	ErbB Receptors (EGF Receptor)IBA 03/2024
1	Biomarkers (Surrogate Marker)IBA 03/2024
1	osimertinibIBA 03/2024
1	CarboxypeptidasesIBA 01/2024
1	Antitubercular AgentsIBA 01/2024
1	Stearoyl-CoA DesaturaseIBA 05/2023
1	Monounsaturated Fatty AcidsIBA 05/2023
1	Fatty Acids (Saturated Fatty Acids)IBA 05/2023
1	Small Interfering RNA (siRNA)IBA 01/2023
1	PolyketidesIBA 01/2023
1	Monoclonal AntibodiesIBA 11/2022
1	Therapeutic UsesIBA 11/2022
1	Membrane Proteins (Integral Membrane Proteins)IBA 11/2022
1	Immune Checkpoint ProteinsIBA 11/2022
1	Immune Checkpoint InhibitorsIBA 11/2022
1	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 05/2022
1	Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA 03/2022

Therapy/Procedure

8	Therapeutics 11/2022 - 03/2012
4	Acupuncture Points (Acupuncture Point) 01/2021 - 11/2017
3	Chemoprevention 05/2024 - 05/2020
1	Immunotherapy 11/2022
1	Personal Protective Equipment 02/2022